Product Detail
                                
                                                                        Product NameVEGFR2(Ab-1175) Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                                                                PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. 
                                        ApplicationsWB IHC IF
                                        Species ReactivityHu
                                        SpecificityThe antibody detects endogenous level of total VEGFR2 protein.
                                        Immunogen TypePeptide-KLH
                                         Immunogen DescPeptide sequence around aa.1173~1177 (K-D-Y-I-V) derived from Human VEGFR2.
                                         Target NameVEGFR2
                                         ConjugateUnconjugated
                                                                                 Other NamesFLK1; KDR; VGFR2; VGR2; kinase insert domain receptor
                                        Accession NoSwiss-Prot: P35968
NCBI Protein: NP_002244.1
                                        Uniprot
                                        P35968
                                        
                                        Gene ID
                                        3791;
                                        
                                                                                                                        Concentration1.0mg/ml
                                         FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. 
                                        StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use. 
                                                                                                                                                         
                                Application Details
                                Predicted MW: 230kd
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200
                             
                            
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using VEGFR2(Ab-1175) Antibody #21077(left) or the same antibody preincubated with blocking peptide(right).
                                 
                                                                
                                    
                                    Immunofluorescence staining of methanol-fixed MCF cells using VEGFR2(Ab-1175) Antibody #21077.
                                 
                                                             
                            
                                Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
Lamalice L, et al. (2004). Oncogene.23(2): 434-445.
Takahashi T, et al. (2001). EMBO J .20(11): 2768-2778.
                            
                            
                                If you have published an article using product 21077, please notify us so that we can cite your literature.