Product Detail
Product NameCDK2(Ab-160) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsWB
Species ReactivityHu Ms Rt
SpecificityThe antibody detects endogenous level of total CDK2 protein.
Immunogen TypePeptide-KLH
Immunogen DescPeptide sequence around aa.158~162 (T-Y-T-H-E) derived from Human CDK2.
Target NameCDK2
ConjugateUnconjugated
Other Nameskinase Cdk2; p33 protein kinase;
Accession NoSwiss-Prot: P24941
NCBI Protein: NP_001789.2
Uniprot
P24941
Gene ID
1017;
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Predicted MW: 34kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from 293, MCF, 3T3 cells using CDK2(Ab-160) Antibody #21111.
Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
Ukomadu C, et al.(2003) J Biol Chem; 278(7): 4840-6
Morris MC, et al.(2002)J Biol Chem; 277(26): 23847-53
Brown NR, et al.(1999)J Biol Chem; 274(13): 8746-56
Liu Y, et al.(2004) J Biol Chem; 279(6): 4507-14
If you have published an article using product 21111, please notify us so that we can cite your literature.
et al,FAM129B/MINERVA, a novel adherens junction-associated protein, suppresses apoptosis in HeLa cells. In J Biol Chem on 2011 Mar 25 by Song Chen, Hedeel Guy Evans, et al..PMID: 21148485
, (2011),
PMID:
21148485
et al,Pro-Apoptotic Effects of JDA-202, a Novel Natural Diterpenoid, on Esophageal Cancer Through Targeting Peroxiredoxin I.In Antioxid Redox Signal on 2017 Jul 10 by Xiao-Jing Shi , Lina Ding,et al..PMID: 27650197
, (2017),
PMID:
27650197
Yes
