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PLCg1(Ab-783) Antibody#21129

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Product Detail

Product NamePLCg1(Ab-783) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total PLCg1 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa. 781~785 (G-F-Y-V-E) derived from Human PLCg1.

Target NamePLCg1

ConjugateUnconjugated

Other NamesPhosphoinositide phospholipase C; Phospholipase C-gamma-1;

Accession NoSwiss-Prot: P19174
NCBI Protein: NP_002651.2

Uniprot P19174

Gene ID 5335;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details
Predicted MW: 155kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from Hela and 293 cells using PLCg1(Ab-783) Antibody #21129.
PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

DeBell KE, et al. Mol Cell Biol. 1999 Nov; 19(11): 7388-7398.
Ver

If you have published an article using product 21129, please notify us so that we can cite your literature.

et al,Signal regulatory protein 伪 negatively regulates mast鈥恈ell activation following Fc蔚RI aggregation. In Eur J Immunol on 2013 Jun by Yu-fei Pan, Li-wei Dong, et al..PMID: 23504624 , (2013),
PMID: 23504624
et al,Discovery of a novel inhibitor of the protein tyrosine phosphatase Shp2.In Sci Rep on 2015 Dec 2 by Chuan Chen , Mengmeng Cao et al..PMID: 26626996 , (2015),
PMID: 26626996
et al,Inhibition of vascular smooth muscle cell proliferation of vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: Pivotal role of hydroxyl radical-mediated PLC 1 and JAK2 phosphorylation. , (2010),
PMID: 20600839
et al,Inhibition of vascular smooth muscle cell proliferation by the vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: pivotal role of hydroxyl radical-mediated PLC 1 and JAK2 phosphorylation. In Free Radic Biol Med on 2010 Sep 1 by Chien-Liang Liu, Ming-Jen Hsu, et al..PMID: 20600839 , (2010),
PMID: 20600839

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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