Product Detail
Product NameFKHRL1(Ab-253) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsWB
Species ReactivityHu Ms Rt
SpecificityThe antibody detects endogenous level of total FKHRL1 protein.
Immunogen TypePeptide-KLH
Immunogen DescPeptide sequence around aa.251~255(A-V-S-M-D) derived from Human FKHRL1.
Target NameFKHRL1
ConjugateUnconjugated
Other NamesFOXO3A; FOXO2;
Accession NoSwiss-Prot: O43524
NCBI Protein: NP_001446.1
Uniprot
O43524
Gene ID
2309;
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Predicted MW: 97kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from 3T3, MCF and 293 cells using FKHRL1(Ab-253) Antibody #21171.
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.
Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., Hu L.S., Anderson M.J., Arden K.C., Blenis J., Greenberg M.E.Cell 96:857-868(1999)
Lehtinen M.K., Yuan Z., Boag P.R., Yang Y., Villen J., Becker E.B.E., DiBacco S., de la Iglesia N., Gygi S.P., Blackwell T.K., Bonni A.Cell 125:987-1001(2006)
If you have published an article using product 21171, please notify us so that we can cite your literature.
et al,Glutamate Attenuates IGF-1 Receptor Tyrosine Phosphorylation in Mouse Brain: Possible Significance in Ischemic Brain Damage.In Neurosci Res on 2012 Dec by Chengming Sun, Qian Meng,et al..PMID:23085572
, (2012),
PMID:
23085572
Yes
