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GABRB1(Ab-434) Antibody#21205

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Product Detail

Product NameGABRB1(Ab-434) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB IHC

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total GABRB1 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1.

Target NameGABRB1

ConjugateUnconjugated

Other NamesGABA(A) receptor; GABA(A)R beta-1; GBRB1; GABA-RB;

Accession NoSwiss-Prot: P18505
NCBI Protein: NP_000803.2

Uniprot P18505

Gene ID 2560;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 54kd
Western blotting: 1:500~1:1000

IHC 1:50-1:200

Western blot analysis of extracts from PC12 cells using GABRB1(Ab-434) Antibody #21205 and the same antibody preincubated with blocking peptide.

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding a 4, a 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.

Collins AL, et al. (2006) Neurogenetics ;7(3):167-174.
Ma DQ, et al. (2005) Am J Hum Genet ;77(3):377-388.
Edenberg HJ, et al. (2004) Am J Hum Genet ;74(4):705-714.

If you have published an article using product 21205, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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