Product Detail
Product NameStathmin1(Ab-38) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsWB IHC IF
Species ReactivityHu Rt
SpecificityThe antibody detects endogenous level of total Stathmin 1 protein.
Immunogen TypePeptide-KLH
Immunogen DescPeptide sequence around aa. 36~40 (P-L-S-P-P) derived from Human Stathmin 1.
Target NameStathmin1
ConjugateUnconjugated
Other NamesSTMN1; STN1; stathmin
Accession NoSwiss-Prot: P16949
NCBI Protein: NP_001138926.1
Uniprot
P16949
Gene ID
3925;
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Predicted MW: 19kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200
Western blot analysis of extracts from 293 and Hela cells using Stathmin 1(Ab-38) Antibody #21218.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1(Ab-38) Antibody #21218(left) or the same antibody preincubated with blocking peptide(right).
Immunofluorescence staining of methanol-fixed Hela cells using Stathmin 1(Ab-38) Antibody #21218.
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
Wang KK, et al. (1991) Biochem J 279(Pt 2): 537-544.
Sekimoto T, et al. (2004) EMBO J 23(9): 1934-1942.
Doye V, et al. (1992) Biochem J 287(Pt 2): 549-554.
Larsson N, et al. (1999) Mol Cell Biol 19(3): 2242-2250.
If you have published an article using product 21218, please notify us so that we can cite your literature.