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CPI17a(Ab-38) Antibody#21281

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Product Detail

Product NameCPI17a(Ab-38) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsIF

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total CPI17a protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa.36~40 (R-V-T-V-K) derived from Human CPI17a.

Target NameCPI17a

ConjugateUnconjugated

Other NamesCPI; CPI-17; CPI17; PP14A;

Accession NoSwiss-Prot: Q96A00
NCBI Protein: NP_150281.1

Uniprot Q96A00

Gene ID 94274;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details
Predicted MW: 17kd
Immunofluorescence: 1:100~1:200
Immunofluorescence staining of methanol-fixed Hela cells using CPI17a(Ab-38) Antibody #21281.
Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

Hagerty L, et al. (2007) J Biol Chem. 2007; 282(7):4884-93
Seok YM, et al. (2008) J Pharmacol Exp Ther.
Niiro N et al. (2003) Biochem J. 2003 ;369(Pt 1):117-28

If you have published an article using product 21281, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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