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PRL-3 Antibody#21333

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Product Detail

Product NamePRL-3 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityThe antibody detects transfected PRL-3 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa. 161-166 (K-D-P-H-T) derived from Human PTP4A3.

Target NamePRL-3

ConjugateUnconjugated

Other Namesprotein tyrosine phosphatase type IVA; PRL3; PRL-R; PTP4A3;

Accession NoSwiss-Prot: O75365
NCBI Protein: NP_116000

Uniprot O75365

Gene ID 11156;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details
Predicted MW: 22kd
Western blotting: 1:500~1:1000
Western blot analysis of extract from LX-2 cells transfected with PRL-3 using PRL-3 antibody #21333.
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.

Matter W.F. et.al. Biochem. Biophys. Res. Commun. 283:1061-1068(2001)
Wang J.et.al. J. Biol. Chem. 277:46659-46668(2002)

If you have published an article using product 21333, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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