Product Detail
Product NameNiban Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsWB IF
Species ReactivityHu
SpecificityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using
epitope-specific immunogen.
Immunogen TypePeptide-KLH
Immunogen Descpeptide sequence around aa. 912~916 (K-E-G-E-G) derived from Human Niban.
Target NameNiban
ConjugateUnconjugated
Other NamesFAM129A
Accession NoSwiss-Prot: Q9BZQ8
NCBI Protein: NP_443198.1
Uniprot
Q9BZQ8
Gene ID
116496;
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Predicted MW: 150kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200
Western blot analysis of extracts from A431 and DU145 cells using Niban Antibody #21401.
Immunofluorescence staining of methanol-fixed Hela cells using Niban Antibody #21401.
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response
Vill
If you have published an article using product 21401, please notify us so that we can cite your literature.
et al,AKT鈥恉ependent phosphorylation of Niban regulates nucleophosmin鈥恆nd MDM2鈥恗ediated p53 stability and cell apoptosis. In EMBO Rep on 2012 Jun 1 by Haitao Ji, Zhiyong Ding, et al..PMID: 22510990
, (2012),
PMID:
22510990
et al,Overexpression of zinc鈥恌inger protein 777 (ZNF777) inhibits proliferation at low cell density through down鈥恟egulation of FAM129A.In J Cell Biochem on 2015 Jun by Ryuzaburo Yuki, Kazumasa Aoyama et al..PMID:25560148
, (2015),
PMID:
25560148
et al,Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming. In Oncotarget on 2016 Oct 11 by Irene Riz, Teresa S Hawley,et al..PMID: 27626179
, (2016),
PMID:
27626179
Yes
