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TRPC6 Antibody#21403

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Product Detail

Product NameTRPC6 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse,Rat

SpecificityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen TypePeptide-KLH

Immunogen DescA synthetic peptide of human TRPC6 (NP_004612.2).

Target NameTRPC6

ConjugateUnconjugated

Other NamesTRPC6;FSGS2;TRP6

Accession NoUniprot:Q9Y210
GeneID:7225

Uniprot Q9Y210

Gene ID 7225

Sdspage MW106KDa

Concentration1.0mg/ml

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of Mouse pancreas, using TRPC6 antibody.
Western blot analysis of extracts of Rat brain, using TRPC6 antibody.
Immunohistochemistry of paraffin-embedded mouse kidney using TRPC6 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human esophageal cancer using TRPC6 Rabbit pAb.
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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