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PP2A-a Antibody#21405

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Product Detail

Product NamePP2A-a Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen TypePeptide-KLH

Immunogen DescPeptide Corresponding to the amino terminal sequence derived from human PP2A-alpha.

Target NamePP2A-a

ConjugateUnconjugated

Other NamesPR52A; PR55A; B55A; B55ALPHA;

Accession NoSwiss-Prot: P67775
NCBI Protein: NP _001171062.1

Uniprot P67775

Gene ID 5515;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 40kd
Western blotting: 1:500~1:1000

Western blot analysis of extracts from C6 cells using PP2A-alpha antibody #21405.
Western blot analysis of extracts from 293T、A431 and BT474 cells using PP2A-alpha antibody #21405.
Western blotting analysis using PP2A-a Antibody #21405.

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Yu, X.X. et al. (2001) Mol. Biol. Cell 12, 185-199.
Tolstykh, T. et al. (2000) EMBO J. 19, 5682-5691.
Janssens, V. and Goris, J. (2001) Biochem. J. 353, 417-439.

If you have published an article using product 21405, please notify us so that we can cite your literature.

et al,Involvement of SET in the Wnt signaling pathway and the development of human colorectal cancer.In Oncol Lett.On 2014 Apr by LEI DONG, JIANJUN ZHU et al..PMID: 24944693 , (2014),
PMID: 24944693

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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