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Lymphatic vessel endothelial hyaluronic acid receptor 1 Antibody#21407

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Product Detail

Product NameLymphatic vessel endothelial hyaluronic acid receptor 1 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total Lymphatic vessel endothelial hyaluronic acid receptor 1 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa.271~275 (K-N-Q-Q-K) derived from Human Lymphatic vessel endothelial hyaluronic acid receptor 1.

Target NameLymphatic vessel endothelial hyaluronic acid receptor 1

ConjugateUnconjugated

Other NamesLYVE1

Accession NoSwiss-Prot: Q9Y5Y7
NCBI Protein: NP_006682.2

Uniprot Q9Y5Y7

Gene ID 10894;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details
Predicted MW: 40kd
Western blotting: 1:500~1:1000
Western blot analysis of extracts from MCF cells using Lymphatic vessel endothelial hyaluronic acid receptor 1 Antibody #21407 and the same antibody preincubated with blocking peptide.
Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Heindl LM, et al. (2010) Ophthalmology.117(2):334-42.
He P et al.(2006) Lin Chuang Er Bi Yan Hou Ke Za Zhi.20(18):828-30, 833.
Lim HY,et al. (2009) Am J Pathol.175(3):1328-37.

If you have published an article using product 21407, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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