Product Detail
Product NameVimentin Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsWB IF
Species ReactivityHu Ms Rt Mk
SpecificityThe antibody detects endogenous level of total Vimentin protein.
Immunogen TypePeptide-KLH
Immunogen DescPeptide sequence around aa.452~456(G-Q-V-I-N) derived from Human Vimentin.
Target NameVimentin
ConjugateUnconjugated
Other NamesCTRCT30
Accession NoSwiss-Prot: P08670
NCBI Protein: NP_003371.2
Uniprot
P08670
Gene ID
7431;
Sdspage MW57kd
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Predicted MW: 57kd
Western blotting: 1:500~1:1000
Immunofluorescence: 1:100~1:200
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
Sommers C.L., Walker-Jones D., Heckford S.E., Worland P., Valverius E., Clark R., McCormick F.,
Cancer Res. 49:4258-4263(1989)
Kang S.-M., Shin M.-J., Kim J.-H., Oh J.-W. Proteomics 5:2227-2237(2005)
Ahmed B.A., Bukhari I.A., Jeffus B.C., Harney J.T., Thyparambil S., Ziu E., Fraer M., Rusch N.J. PLoS ONE 4:E4730-E4730(2009)
If you have published an article using product 21488, please notify us so that we can cite your literature.
et al,Foxg1 Has an Essential Role in Postnatal Development of the Dentate Gyrus.
, (2012),
PMID:
22378868
et al,Exosomal miR 423 5p targets SUFU to promote cancer growth and metastasis and serves as a novel marker for gastric cancer.In Mol Carcinog. On 2018 Sep by Yang H, Fu H et al..PMID:29749061
, (2018),
PMID:
29749061
et al,Exosomal TRIM3 is a novel marker and therapy target for gastric cancer.In J Exp Clin Cancer Res.On 2018 Jul 21 by Fu H, Yang H et al..PMID:30031392
, (2018),
PMID:
30031392
et al,Baicalein Inhibits Migration and Invasion of Gastric Cancer Cells Through Suppression of the TGF-尾 Signaling Pathway.In Mol Med Rep on 2014 Oct by Fenglin Chen, Mingkai Zhuang et al..PMID: 25109410
, (2014),
PMID:
25109410
et al,Activation of mesenchymal stem cells by macrophages prompts human gastric cancer growth through NF-魏B pathway.In PLoS One on 2014 May 13 by Tingting Yang , Xu Zhang et al..PMID:24824968
, (2014),
PMID:
24824968
et al,SALL4, a novel marker for human gastric carcinogenesis and metastasis.In Oncogene on 2014 Nov 27 by L Zhang , Z Xu et al..PMID:24276240
, (2014),
PMID:
24276240
et al,Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness.In BMC Cancer on 2015 Oct 24 by Jianguo Xue , Yuan Zhu et al..PMID: 26498753
, (2015),
PMID:
26498753
More
et al, Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression.In Int J Oncol on 2014 Mar by Hai Zhang, Shanyu Cheng, et al..PMID: 24378923
, (2016),
PMID: 24378923
et al,Ginsenoside Rg3 Suppresses Epithelial-Mesenchymal Transition via Downregulating Notch-Hes1 Signaling in Colon Cancer Cells. In Am J Chin Med on 2021 by Xiao Li, Wei Liu, et al..PMID:33371813
, (2021),
PMID: 33371813
et al,Qingda granule attenuates cardiac fibrosis via suppression of the TGF-尾1/Smad2/3 signaling pathway in vitro and in vivo. In Biomed Pharmacother on 2021 May by Xiaoping Chen, Linzi Long, et al..PMID:33556875
, (2021),
PMID: 33556875
et al,Flotillin-1 enhances radioresistance through reducing radiation-induced DNA damage and promoting immune escape via STING signaling pathway in non-small cell lung cancerInCancer Biol TherOn2023 Dec 31byYingying Wang?1,?Lu Meng et al..PMID:?37131290
, (2023),
PMID: 37131290
et al,HIV gp120/Tat protein-induced epithelial-mesenchymal transition promotes the progression of cervical lesionsInAIDS Res TherOn2023 Nov 19byPeizhi Wang?#?1?2,?Baojun Yang et al..PMID:?37981694
, (2023),
PMID: 37981694
et al,Qingda granule ameliorates vascular remodeling and phenotypic transformation of adventitial fibroblasts via suppressing the TGF-β1/Smad2/3 pathwayIn J EthnopharmacolOn2023 Sep 15byMeizhu Wu , Siyu Zhang et al..PMID:37100260
, (2023),
PMID: 37100260
et al,A Novel Airway-Organoid Model Based on a Nano-Self-Assembling Peptide: Construction and Application in Adenovirus Infection StudiesIn Int J NanomedicineOn2023 Sep 13byYun-E Xu , Di-Shu Ao et al..PMID:37727651
, (2023),
PMID: 37727651