Product Detail
Product NameCDC2(Ab-19) Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous level of total CDC2 protein.
Immunogen TypePeptide-KLH
Immunogen DescPeptide sequence around aa.17~21 (V-V-Y-K-G) derived from Human CDC2.
Target NameCDC2
ConjugateUnconjugated
Other NamesCDC28; CDC2A; CDK1; Cyclin-dependent kinase 1;
Accession NoSwiss-Prot: P06493
NCBI Protein: NP_001163877.1
Uniprot
P06493
Gene ID
983;
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Predicted MW: 34kd
Immunohistochemistry: 1:50~1:100
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CDC2(Ab-19) Antibody #21529(left) or the same antibody preincubated with blocking peptide(right).
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
Hunter, T. (1995) Cell 80, 225-236.
Wells, N.J. et al. (1999) J. Cell. Sci. 112, 3361-3371.
McGowan, C.H. and Russell, P. (1993) EMBO J. 12, 75-85.
If you have published an article using product 21529, please notify us so that we can cite your literature.
Yes
