Product Detail
                                
                                                                        Product NameFOXP2 Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                                                                PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. 
                                        ApplicationsWB
                                        Species ReactivityHu Ms Rt
                                        SpecificityThe antibody detects endogenous level of total FOXP2 protein.
                                        Immunogen TypePeptide-KLH
                                         Immunogen DescPeptide sequence around aa.707~711(E-E-P-L-S) derived from Human FOXP2.
                                         Target NameFOXP2 
                                         ConjugateUnconjugated
                                                                                 Other NamesSPCH1; CAGH44; TNRC10
                                        Accession NoSwiss-Prot: O15409
NCBI Protein: NP_055306.1
                                        Uniprot
                                        O15409
                                        
                                        Gene ID
                                        93986;
                                        
                                                                                                                        Concentration1.0mg/ml
                                         FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
                                        StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use. 
                                                                                                                                                         
                                Application Details
                                Predicted MW: 85kd
Western blotting: 1:500~1:1000
                             
                            
                                                                
                                    
                                    Western blot analysis of extract from JK, Raji and 293 cells using FOXP2 Antibody #21608
                                 
                                                             
                            
                                Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Involved in neural mechanisms mediating the development of speech and language.
Bruce H.A., Margolis R.L.Hum. Genet. 111:136-144(2002) Teramitsu I., Kudo L.C., London S.E., Geschwind D.H., White S.A.J. Neurosci. 24:3152-3163(2004) 
                            
                            
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