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CRABP2 Antibody#21647

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Product Detail

Product NameCRABP2 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB

Species ReactivityHu Rt

SpecificityThe antibody detects endogenous levels of total CRABP2 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa.87~91(K-W-E-S-E) derived from Human CRABP2

Target NameCRABP2

ConjugateUnconjugated

Other NamesRBP6; CRABP-II;

Accession NoSwiss-Prot: P29373
NCBI Protein: NP_001186652.1

Uniprot P29373

Gene ID 1382;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 16kd
Western blotting: 1:500~1:1000
 

Western blot analysis of extracts from MCF-7 and HT-29 cells using CRABP2 Antibody #21647.

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors "Direct channeling of retinoic acid between cellular retinoic acid-binding protein II and retinoic acid receptor sensitizes mammary carcinoma cells to retinoic acid-induced growth arrest."

Budhu A.S., Noy N. Mol. Cell. Biol. 22:2632-2641(2002) "A ligand-activated nuclear localization signal in cellular retinoic acid binding protein-II."
Sessler R.J., Noy N. Mol. Cell 18:343-353(2005)

If you have published an article using product 21647, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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