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CUEDC2 Antibody#21673

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Product Detail

Product NameCUEDC2 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

ApplicationsWB

Species ReactivityHu Ms

SpecificityThe antibody detects endogenous level of total CUEDC2 protein.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around aa.262~266(D-V-R-N-P) derived from Human CUEDC2.

Target NameCUEDC2

ConjugateUnconjugated

Other NamesC10orf66; bA18I14.5;

Accession NoSwiss-Prot: Q9H467
NCBI Protein: NP_076945.2

Uniprot Q9H467

Gene ID 79004;

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

Predicted MW: 32kd
Western blotting: 1:500~1:1000
 

Western blot analysis of extracts from HepG2, Hela and 293 cells using CUEDC2 Antibody #21673.

Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.

Zhang P.-J., Zhao J., Li H.-Y. EMBO J. 26:1831-1842(2007)

If you have published an article using product 21673, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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