Product Detail
Product NamePANK1 antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationPurified by antigen-affinity chromatography.
ApplicationsWB IHC IF
Species ReactivityHu
Immunogen TypeRecombinant protein
Immunogen DescRecombinant protein fragment contain a sequence corresponding to a region within amino acids 207 and 483 of Human PANK1
Target NamePANK1
ConjugateUnconjugated
Accession NoSwiss-Prot:Q8TE04
Gene ID:53354
Uniprot
Q8TE04
Gene ID
53354;
Concentration1mg/ml
FormulationSupplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details
Predicted MW: 64kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:50-1:500
Immunofluorescence: 1:100-1:200
Sample(30 ug whole cell lysate)
A: Hep G2
7.5% SDS PAGE
Primary antibody diluted at 1: 5000
Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using PANK1 antibody at 1: 500 dilution.
Immunofluorescence analysis of methanol-fixed Hep G2, using PANK1 antibody at 1: 500 dilution.
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified. [provided by RefSeq]
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