Product Detail
Product NameThrombomodulin(CD141) antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationPurified by antigen-affinity chromatography.
ApplicationsWB IF
Species ReactivityHu
Immunogen TypePeptide
Immunogen DescSynthetic peptide contain a sequence corresponding to a region within amino acids 512 and 575 of Thrombomodulin(CD141)
Target NameThrombomodulin(CD141)
ConjugateUnconjugated
Other NamesTM; THRM; CD141
Accession NoSwiss-Prot:P07204
Gene ID:7056
Uniprot
P07204
Gene ID
7056;
Concentration1mg/ml
FormulationSupplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details
Predicted MW: 60kd
Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:200
Sample (30 ug of whole cell lysate)
A: THP-1
7.5% SDS PAGE
Primary antibody diluted at 1: 500
Immunofluorescence analysis of paraformaldehyde-fixed A549, using Thrombomodulin(CD141) antibody at 1: 200 dilution.
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq]
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