Product Detail
Product NameRAP1A antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationPurified by antigen-affinity chromatography.
ApplicationsWB
Species ReactivityHu
Immunogen TypeRecombinant protein
Immunogen DescRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 154 of RAP1A
Target NameRAP1A
ConjugateUnconjugated
Other NamesRAP1; KREV1; KREV-1; SMGP21
Accession NoNCBI Gene ID: 5906
NCBI mRNA#: NM_001010935
NCBI Protein#: NP_001010935
Uniprot
P62834
Gene ID
5906;
Concentration0.5mg/ml
FormulationSupplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details
Predicted MW: 21kd
Western blotting: 1:500-1:3000
Sample (30 ug of whole cell lysate)
A: Molt-4
12% SDS PAGE
RAP1A antibody diluted at 1: 1000
The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq]
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