Product Detail
Product NameRAPGEF5 antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationPurified by antigen-affinity chromatography.
ApplicationsWB
Species ReactivityHu
Immunogen TypeRecombinant protein
Immunogen DescRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 179 of Human RAPGEF5
Target NameRAPGEF5
ConjugateUnconjugated
Other NamesGFR; KIAA0277; MR-GEF; REPAC
Accession NoSwiss-Prot:Q92565
Gene ID:9771
Uniprot
Q92565
Gene ID
9771;
Concentration0.7mg/ml
FormulationSupplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details
Predicted MW: 85kd
Western blotting: 1:500-1:3000
Sample(30 ug of whole cell lysate)
A: HeLa S3
7.5% SDS PAGE
Primary antibody diluted at 1: 1000
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]
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