Product Detail
Product NameDPYD antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationPurified by antigen-affinity chromatography.
ApplicationsWB
Species ReactivityHu
Immunogen TypeRecombinant protein
Immunogen DescRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 144 of DPYD
Target NameDPYD
ConjugateUnconjugated
Accession NoSwiss-Prot:Q12882
Gene ID:1806
Uniprot
Q12882
Gene ID
1806;
Concentration0.6mg/ml
FormulationSupplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details
Predicted MW: 19kd
Western blotting: 1:500-1:3000
Sample (30 ug of whole cell lysate)
A: H1299
12% SDS PAGE
DPYD antibody diluted at 1: 500
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. [provided by RefSeq]
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