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Location： Home > Polyclonal Antibodies > NKG2-A(CD159a) antibody

NKG2-A(CD159a) antibody#22434

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Product Detail

Product NameNKG2-A(CD159a) antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationPurified by antigen-affinity chromatography.

ApplicationsWB IF

Species ReactivityHu

Immunogen TypePeptide

Immunogen DescSynthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of NKG2-A (CD159a)

Target NameNKG2-A(CD159a)

ConjugateUnconjugated

Other NamesCD159A; MGC13374; MGC59791; NKG2; NKG2A

Accession NoSwiss-Prot:P26715
Gene ID:3821

Uniprot P26715

Gene ID 3821;

Concentration1.64 mg/ml

FormulationSupplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.

StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.

Application Details

Predicted MW: 26kd
Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:200

Sample (30 ug of whole cell lysate)
A: A431
B: Hep G2
12% SDS PAGE
NKG2-A (CD159a) antibody diluted at 1: 1000
Immunofluorescence analysis of methanol-fixed HeLa, using KLRC1 antibody at 1: 200 dilution.

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq]

If you have published an article using product 22434, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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