Product Detail
Product NameRAMP2 antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationPurified by antigen-affinity chromatography.
ApplicationsWB IHC
Species ReactivityHu
Immunogen TypePeptide
Immunogen DescSynthetic peptide contain a sequence corresponding to a region within amino acids 111 and 175 of Human RAMP2
Target NameRAMP2
ConjugateUnconjugated
Accession NoSwiss-Prot:O60895
Gene ID:10266
Uniprot
O60895
Gene ID
10266;
Concentration1mg/ml
FormulationSupplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
StorageStore at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Application Details
Predicted MW: 20kd
Western blotting: 1:500-1:3000
Immunohistochemistry: 1:100-1:250
Sample(30 ug of whole cell lysate)
A: MOLT4
B: Raji
12% SDS PAGE
Primary antibody diluted at 1: 1500
Immunohistochemical analysis of paraffin-embedded SG xenograft, using RAMP2 antibody at 1: 100 dilution.
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq]
If you have published an article using product 22553, please notify us so that we can cite your literature.
Yes
