Product Detail
                                
                                                                        Product NameCD4 Monoclonal Antibody
                                        Clone No.mAb (Clone 9H5A8)
                                         Host SpeciesMouse
                                         ClonalityMonoclonal
                                                                                PurificationImmunoaffinity chromotography purified IgG
                                        ApplicationsELISA WB
                                        Species ReactivityHu Ms Rt
                                                                                Immunogen TypeRecombinant protein
                                         Immunogen DescRaised against  a 193 amino acid recombinant protein from near the amino terminus of human CD4.
                                         Target NameCD4 
                                         ConjugateUnconjugated
                                                                                 Other NamesCD4 (9H5A8), CD4 antigen, CD4 receptor
                                        Accession NoSwiss-Prot:P01730
Gene ID:920
                                        Uniprot
                                        P01730
                                        
                                        Gene ID
                                        920;
                                        
                                                                                                                        Concentration1mg/ml
                                         FormulationSupplied in PBS containing 0.02% sodium azide.
                                        StorageCan be stored at -20˚C, stable for one year.
                                                                                                                                                         
                                Application Details
                                
                             
                            
                                                                
                                    
                                    Western blot analysis of CD4 in human thymus tissue lysate with CD4 antibody at (A) 0.5 and (B) 1 ug/mL.
                                 
                                                                
                                    
                                    Immunohistochemistry of CD4 in human thymus tissue with CD4 antibody at 5 μg/ml.
                                 
                                                             
                            
                                CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
                            
                            
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