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BARK1 Monoclonal Antibody#27101

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Product Detail

Product NameBARK1 Monoclonal Antibody

Clone No.3F8-G6-C11

Host SpeciesMouse

ClonalityMonoclonal

IsotypeIgG1

PurificationAffinity purified

ApplicationsELISA WB

Species ReactivityHu Rt Ms P D

Immunogen TypeRecombinant protein

Immunogen DescPurified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.

Target NameBARK1

ConjugateUnconjugated

Other NamesGRK2, BARK1, BETA-ARK1

Accession NoSwiss-Prot:P13639
Gene ID:1938

Uniprot P13639

Gene ID 1938;

FormulationPurified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Application Details
Predicted MW: 80kd
Western blotting: 1:1000
Western blot detection of ADRBK1 in U937,Raw264.7&Ramos whole cell lysate(1:1000 diluted)
Predicted band size:80KDa.
Observed band size:80KDa.
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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