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CHRDL1 Monoclonal Antibody#27106

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Product Detail

Product NameCHRDL1 Monoclonal Antibody

Clone No.3H1-F6-A10

Host SpeciesMouse

ClonalityMonoclonal

IsotypeIgG1

PurificationAffinity purified

ApplicationsELISA WB

Species ReactivityHu Rt

Immunogen TypeRecombinant Protein

Immunogen DescPurified recombinant human CHRDL1 protein fragments expressed in E.coli.

Target NameCHRDL1

ConjugateUnconjugated

Other NamesCHL, VOPT, NRLN1, dA141H5.1

Accession NoSwiss-Prot:P12532
Gene ID:1159

Uniprot Q9BU40

Gene ID 91851

FormulationPurified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Application Details

Predicted MW: 57kd
Western blotting: 1:1000

Western blot detection of CHRDL1 in Rat kidney tissue lysates using CHRDL1 antibody (1:1000 diluted).
Predicted band size: 57kDa
Observed band size: 57kDa
Immunocytochemistry stain of Hela using CHRDL1 antibody (1:300).

This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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