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Location： Home > Mouse Monoclonal Antibodies > PP1C Monoclonal Antibody

PP1C Monoclonal Antibody#27177

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Product Detail

Product NamePP1C Monoclonal Antibody

Clone No.2F2-A3-H10

Host SpeciesMouse

ClonalityMonoclonal

IsotypeIgG2b

PurificationAffinity purified

ApplicationsWB

Species ReactivityHu

SpecificityThis antibody detects endogenous levels of PPP1CC and does not cross-react with related proteins.

Immunogen TypeRecombinant Protein

Immunogen DescPurified recombinant human PPP1CC protein fragments expressed in E.coli.

Target NamePP1C

ConjugateUnconjugated

Other NamesEC 3.1.3.16; PP 1G; PP-1G; PP1G; PP1G_HUMAN; PP1gamma; PPP 1G; PPP1CC; PPP1CC protein; PPP1G; Protein phosphatase 1 catalytic subunit gamma isoform; Protein phosphatase 1C catalytic subunit; Protein phosphatase 1C subunit

Accession NoUniprot: P36873

Gene ID: 5501

Uniprot P36873

Gene ID 5501;

Sdspage MW38kd

FormulationPurified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.2% sodium azide,0.1mg/mlBSA and 50% glycerol.

Storagestore at -20˚C

Application Details

 Western blotting: 1:500

Western blot detection of PPP1CC antibody in Hela,293T and Jurkat cell lysates using PPP1CC antibody (1:500 diluted).Predicted band size:38KDa.Observed band size:38KDa.

 Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.Protein phosphatase 1(PP1)is essential for cell division,and participates in the regulation of glycogen metabolism,muscle contractility and protein synthesis.Dephosphorylates RPS6KB1.Involved in regulation of ionic conductances and long-term synaptic plasticity.May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.Component of the PTW/PP1 phosphatase complex,which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

If you have published an article using product 27177, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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