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CBR1 Monoclonal Antibody#27187

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Product Detail

Product NameCBR1 Monoclonal Antibody

Clone No.2C9-B12-C4

Host SpeciesMouse

ClonalityMonoclonal

IsotypeIgG1

PurificationAffinity purified

ApplicationsWB ICC

Species ReactivityHu

SpecificityThis antibody detects endogenous levels of CBR1,and does not cross-react with related proteins.

Immunogen TypeRecombinant Protein

Immunogen DescPurified recombinant human CBR1 protein fragments expressed in E.coli

Target NameCBR1

ConjugateUnconjugated

Other Names15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;

Accession NoUniprot: P16152

Gene ID: 873

Uniprot P16152

Gene ID 873;

Sdspage MW30kd

FormulationPurified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.

Storagestore at -20˚C

Application Details

Western blotting: 1:1000

Immunocytochemistry: 1:100
Immunocytochemistry stain of Hela using CBR1 antibody (1:100).
Western blot detection of CBR1 in Hela,A431 & MDA-MB-468 cell lysates using CBR1 antibody(1:1000 diluted).Predicted band size:30KDa,Observed band size:30KDa.

 NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.

If you have published an article using product 27187, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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