Product Detail
Product NameIKB alpha Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human IKB alpha (NP_065390.1).
ConjugateUnconjugated
Other NamesNFKBIA; IKBA; MAD-3; NFKBI; NFKB inhibitor alpha
Accession NoSwiss-Prot#:P25963
NCBI Gene ID:4792
Uniprot
P25963
Gene ID
4792;
Calculated MW36kDa
FormulationAvoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
IP 1:20 - 1:50
Western blot analysis of extracts of various cell lines, using IKB alpha at 1:1000 dilution.
Western blot analysis of extracts from normal (control) and IKB alpha knockout (KO) 293T cells, using IKB alpha at 1:1000 dilution.
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
If you have published an article using product 27531, please notify us so that we can cite your literature.
et al,5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis. In J Atheroscler Thromb on 2021 Feb 2 by Yingying Ma, Xiurui Liang,et al..PMID: 33536397
, (2021),
PMID:
33536397
et al,5-HT2A Receptor and 5-HT Degradation Play a Crucial Role in Atherosclerosis by Modulating Macrophage Foam Cell Formation, Vascular Endothelial Cell Inflammation, and Hepatic Steatosis In J Atheroscler Thromb on 2022 Mar 1 by Yingying Ma, Xiurui Liang,et al..PMID: 33536397
, (2022),
PMID:
33536397
et al,The Effect of Clostridium butyricum-Derived Lipoteichoic Acid on Lipopolysaccharide-Stimulated Porcine Intestinal Epithelial Cells.
, (2025),
PMID:
39749788
Yes
