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Location： Home > Polyclonal Antibodies > ERK1/2 Antibody

ERK1/2 Antibody #29162

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Product Detail

Product NameERK1/2 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAffinity-chromatography

ApplicationsWB IHC

Species ReactivityHu Ms Rt

SpecificityERK1/2 antibody detects endogenous levels of total ERK1/2

Immunogen TypePeptide

Immunogen DescA synthesized peptide derived from human ERK1/2

Target NameERK1/2

ConjugateUnconjugated

Other NamesExtracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, Microtubule-associated protein 2 kinase extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kin

Accession NoSwiss-Prot: P27361/P28482
Gene ID:7531

Uniprot P27361/P28482

Gene ID 7531;

Sdspage MW42,44KD

Concentration1.0mg/ml

FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C/1 year

Application Details

 WB: 1:500~1:3000

   IHC: 1:50~1:200 
Western blot analysis on COLO205 cell lysate using ERK1/2 Antibody

ERK1 p42 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters.ERK2 p44 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.

If you have published an article using product 29162, please notify us so that we can cite your literature.

et al,Cardamonin Protects Septic Mice from Acute Lung Injury by Preventing Endothelial Barrier Dysfunction , (2012),
PMID: 22696397
et al,The synergic Inhibitory effects of dark tea (Camellia sInensis) extract and p38 Inhibition on the growth of pancreatic cancer cells. In J Cancer on 2019 Oct 21 by Zheng K, Zhao Q,et al..PMID:31777585 , (2019),
PMID: 31777585
et al,Inhibitory effects of eugenol on RANKL-induced osteoclast formation via attenuation of NF-魏 B and MAPK pathways.In Connect Tissue Res on 2015 Jun by Vishwa Deepak , Abe Kasonga et al..PMID:25405641 , (2015),
PMID: 25405641
et al,Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signalingInMol MedOn2023 Mar 23byXu Cao?1?2,?Song Wu et al..PMID:?36959556 , (2023),
PMID: 36959556
et al,Apatinib inhibits pancreatic cancer growth, migration and invasion through the PI3K/AKT and ERK1/2/MAPK pathways , (2021),
PMID: 35116637

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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