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PINK1 Rabbit Polyclonal Antibody#29297

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Product NamePINK1 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF,IHC

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human PINK1 (NP_115785.1).

ConjugateUnconjugated

Other NamesPINK1;BRPK;PARK6

Accession NoSwiss Prot:Q9BXM7
GeneID:65018

Uniprot Q9BXM7

Gene ID 65018

Calculated MW30kDa/62kDa

Sdspage MW50kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details

WB 1:500 - 1:2000
IF 1:50 - 1:200
IHC 1:50 - 1:200

Immunofluorescence analysis of HeLa cells using PINK1 . Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using PINK1 at 1:1000 dilution.

This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.

If you have published an article using product 29297, please notify us so that we can cite your literature.

et al,Study of mitophagy and ATP-related metabolomics based on β-amyloid levels in Alzheimer's disease. In Exp Cell Res on 2020 Nov 1 by Xiaomin Xiong, Shijie Li, et al..PMID: 32905804 , (2020),
PMID: 32905804
et al,Dietary High-Fat Promotes Cognitive Impairment by Suppressing MitophagyInOxid Med Cell LongevOn2023 Jan 21byOxid Med Cell Longev et al..PMID:?36718278 , (2023),
PMID: 36718278
et al,Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission. In Mol Cell Biochem on 2024 Jul 13 by Haixia Fan, Minghao Yuan,et al..PMID:38997506 , (2024),
PMID: 38997506
et al,Xinyin tablets affect mitophagy and cardiomyocyte apoptosis to alleviate chronic heart failure by regulating histone deacetylase 3(HDAC3)-mediated PTEN induced putative kinase 1(PINK1)/Parkin signaling pathway. , (2025),
PMID: 40122315

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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