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LGR5 Rabbit Polyclonal Antibody#29562

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Product Detail

Product NameLGR5 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB;IHC

Species ReactivityMouse;Rat

Immunogen DescRecombinant fusion protein of human LGR5 (NP_003658.1).

ConjugateUnconjugated

Other NamesLGR5;FEX;GPR49;GPR67;GRP49;HG38

Accession NoSwiss Prot:O75473
GeneID:8549

Calculated MW100kDa

Sdspage MW105kDa

Concentration2.92 mg/mL

FormulationPBS with 0.09% Sodium azide, 50% glycerol, pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:1000 - 1:5000;
IHC-P 1:100 - 1:500
Western blot analysis of lysates from Mouse brain using LGR5/GPR49 Rabbit pAb at 1:2000 dilution.
Immunohistochemistry analysis of paraffin-embedded Rat brain using LGR5/GPR49 Rabbit pAb at dilution of 1:300 (40x lens).
Immunohistochemistry analysis of paraffin-embedded Rat lung using LGR5/GPR49 Rabbit pAb at dilution of 1:300 (40x lens).
Immunohistochemistry analysis of paraffin-embedded Rat ovary using LGR5/GPR49 Rabbit pAb at dilution of 1:300 (40x lens).

The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

If you have published an article using product 29562, please notify us so that we can cite your literature.

et al,Dietary emulsifier Polysorbate 80-induced lipotoxicity promotes intestinal senescence , (2025),
PMID:

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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