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Location： Home > Polyclonal Antibodies > IL4 Rabbit Polyclonal Antibody

IL4 Rabbit Polyclonal Antibody#29564

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Product Detail

Product NameIL4 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human IL4 (NP_000580.1).

ConjugateUnconjugated

Other NamesIL4;BCGF-1;BCGF1;BSF-1;BSF1;IL-4

Accession NoSwiss_Prot:P05112
Gene_ID:3565

Uniprot P05112

Calculated MW13kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20℃. Avoid freeze / thaw cycles.

Application Details

WB 1:500 - 1:2000

Western blot analysis of extracts of various cell lines, using IL4 antibody.
Western blot analysis of extracts of rat skeletal muscle, using IL4 antibody.

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. 

If you have published an article using product 29564, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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