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Ghrelin Polyclonal Antibody#29578

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Product NameGhrelin Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

ApplicationsWB IHC-p IF

Species ReactivityHuman Mouse Rat

SpecificityGhrelin Polyclonal Antibody detects endogenous levels of Ghrelin protein.

Immunogen DescThe antiserum was produced against synthesized peptide derived from human Ghrelin. AA range:47-96

ConjugateUnconjugated

Accession NoSwiss-Prot#: Q9UBU3

Uniprot Q9UBU3

Concentration1mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20��/1 year

Application Details

 Western Blot: 1/500 - 1/2000

Immunohistochemistry: 1/100 - 1/300

 

Western Blot analysis of various cells using Ghrelin Polyclonal Antibody
Immunohistochemistry analysis of Ghrelin antibody in paraffin-embedded human lung carcinoma tissue.

 ghrelin and obestatin prepropeptide(GHRL) Homo sapiens This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function

If you have published an article using product 29578, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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