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ANGPT1 Rabbit Polyclonal Antibody#29584

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Product Detail

Product NameANGPT1 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human ANGPT1 (NP_001186788.1).

ConjugateUnconjugated

Other NamesANGPT1;AGP1;AGPT;ANG1

Accession NoSwiss Prot:Q15389
GeneID:284

Calculated MW57kDa

Sdspage MW51kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details

WB 1:500 - 1:2000
IHC 1:50 - 1:100

Western blot analysis of extracts of various cell lines, using ANGPT1 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded rat lung using ANGPT1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using ANGPT1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using ANGPT1 at dilution of 1:100 (40x lens).

This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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