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MYH7 Rabbit Polyclonal Antibody#29592

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Product Detail

Product NameMYH7 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityMouse,Rat

Immunogen DescRecombinant fusion protein of human MYH7 (NP_000248.2).

ConjugateUnconjugated

Other NamesMYH7;CMD1S;CMH1;MPD1;MYHCB;SPMD;SPMM;myosin-7;MYH7

Accession NoSwiss Prot:P12883
GeneID:4625

Calculated MW223kDa

Sdspage MW223kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details

WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200

Immunofluorescence analysis of rat skeletal muscle using MYH7 at dilution of 1:100. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of rat heart, using MYH7 at 1:1000 dilution.
Western blot analysis of extracts of various cell lines, using MYH7 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded mouse skeletal muscle using MYH7 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using MYH7 at dilution of 1:100 (40x lens).

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

If you have published an article using product 29592, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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