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BMPR-II Monoclonal Antibody#29596

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Product Detail

Product NameBMPR-II Monoclonal Antibody

Host SpeciesMouse

ClonalityMonoclonal

ApplicationsWB,IHC-p,IF/ICC

Species ReactivityHuman,Mouse,Rat

Immunogen DescPurified recombinant fragment of human BMPR-II expressed in E. Coli.

ConjugateUnconjugated

Accession NoSwiss-Prot#: Q13873

Uniprot Q13873

Concentration1mg/ml

FormulationAscitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

StorageStore at -20��/1 year

Application Details

 Western Blot: 1/500 - 1/2000
 Immunohistochemistry: 1/200 - 1/1000
Immunofluorescence: 1/200 - 1/1000.

Western Blot analysis using BMPR-II Monoclonal Antibody against HeLa (1), A431 (2), NIH/3T3 (3), Cos7 (4) and PC-12 (5) cell lysate.
Immunohistochemistry analysis of paraffin-embedded muscle tissues (left) and kidney cancer tissues (right) with DAB staining using BMPR-II Monoclonal Antibody.

 bone morphogenetic protein receptor type 2(BMPR2) Homo sapiens This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disea

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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