Product Detail
Product NameITLN1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityMouse,Rat
Immunogen DescRecombinant fusion protein of human ITLN1 (NP_060095.2).
ConjugateUnconjugated
Other NamesITLN1;HL-1;HL1;INTL;ITLN;LFR;hIntL;omentin
Accession NoUniprot:Q8WWA0
GeneID:55600
Uniprot
Q8WWA0
Gene ID
55600
Calculated MW34kDa
Sdspage MW37kDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using ITLN1 antibody.
Immunohistochemistry of paraffin-embedded mouse intestin using ITLN1 Rabbit pAb.
Immunofluorescence analysis of mouse colon using ITLN1 Rabbit pAb.
Immunofluorescence analysis of rat intestine using ITLN1 Rabbit pAb.
Intelectin-1(ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDaCa-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell typesand appears to participate in insulin signaling and microbe recognition. The protein has no effect on basalglucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylationin the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. Italso may specifically recognize carbohydrate chains of pathogens and bacterial components containinggalactofuranosy l residues, in a calcium-dependent manner.
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