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BDNF Rabbit Polyclonal Antibody#29683

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Product Detail

Product NameBDNF Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human BDNF (NP_733928.1).

ConjugateUnconjugated

Other NamesBDNF;ANON2;BULN2

Accession NoSwiss Prot:P23560
GeneID:627

Calculated MW27kDa/28kDa/29kDa/31kDa/37kDa

Sdspage MW15kDa/35kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details

WB 1:500 - 1:2000
IF 1:50 - 1:200

Immunofluorescence analysis of U-251MG cells using BDNF at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Western blot analysis of extracts of U-251MG cells, using BDNF at 1:1000 dilution.
Western blot analysis of extracts of various cell lines, using BDNF at 1:1000 dilution.

This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

If you have published an article using product 29683, please notify us so that we can cite your literature.

et al,Nociceptor-localized KCC2 suppresses brachial plexus avulsion-induced neuropathic pain and related central sensitization. , (2025),
PMID: 39891150

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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