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TXNIP Rabbit Polyclonal Antibody#29687

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Product Detail

Product NameTXNIP Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Rat,Mouse

Immunogen DescRecombinant fusion protein of human TXNIP (NP_006463.3).

ConjugateUnconjugated

Other NamesTXNIP;ARRDC6;EST01027;HHCPA78;THIF;VDUP1

Accession NoSwiss Prot:Q9H3M7
GeneID:10628

Calculated MW37kDa/43kDa

Sdspage MW45kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details

WB 1:200 - 1:2000

Western blot analysis of extracts of various cell lines, using TXNIP at 1:3000 dilution.
Immunofluorescence analysis of U2OS cells using TXNIP antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

If you have published an article using product 29687, please notify us so that we can cite your literature.

et al,Mechanism of mitigating effect of wheat germ peptides on lead-induced oxidative damage in PC12 cells. In Ecotoxicol Environ Saf on 2022 Nov by Ning Li, Liuding Wen, et al..PMID: 36252511 , (2022),
PMID: 36252511

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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