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BGLAP Rabbit Polyclonal Antibody#29697

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Product Detail

Product NameBGLAP Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescA synthetic peptide of human BGLAP (NP_954642.1).

ConjugateUnconjugated

Other NamesBGLAP;BGP;OC;OCN;osteocalcin

Accession NoSwiss Prot:P02818
GeneID:632

Calculated MW11kDa

Sdspage MW11kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details

WB 1:500 - 1:2000

Western blot analysis of extracts of mouse pancreas, using BGLAP at 1:1000 dilution.
Immunofluorescence analysis of MG-63 cells using BGLAP Rabbit pAb at dilution of 1:200. Blue: DAPI for nuclear staining.

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

If you have published an article using product 29697, please notify us so that we can cite your literature.

et al,An electrostatic encapsulation strategy to motivate 3D-printed polyelectrolyte scaffolds for repair of osteoporotic bone defects. , (2025),
PMID: 39719966

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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