Product Detail
Product NameLAP3 Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human LAP3 (NP_056991.2).
ConjugateUnconjugated
Other NamesLAP3;HEL-S-106;LAP;LAPEP;PEPS
Accession NoUniprot:P28838
GeneID:51056
Uniprot
P28838
Gene ID
51056
Calculated MW56kDa
Sdspage MW56kDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using LAP3 antibody.
Cytolosic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+ ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+, it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.
If you have published an article using product 30822, please notify us so that we can cite your literature.
et al,Artemisinin alleviates astrocyte overactivation and neuroinflammation by modulating the IRE1/NF-κB signaling pathway in in vitro and in vivo Alzheimer's disease models.
, (2025),
PMID:
39826816
Yes
