Product Detail
Product NameCBX2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
ApplicationsELISA WB
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous level of total CBX2 protein.
Immunogen TypeRecombinant protein
Immunogen DescFull length fusion protein
Target NameCBX2
ConjugateUnconjugated
Other Nameschromobox homolog 2, M33, CDCA6, SRXY5
Accession NoSwiss-Prot:Q14781
Gene ID:84733;
Uniprot
Q14781
Gene ID
84733;
Concentration0.72mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C/1 year
Application Details
Predicted MW: 23kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Gel: 12+10%SDS-PAGE
Lane1: Human ovarian cancer tissue lysate
Lane2: Mouse heart tissue lysate
Lysates: 30ug per lane
Primary antibody: 1/350 dilution
Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Exposure time: 20 seconds
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
If you have published an article using product 31050, please notify us so that we can cite your literature.
et al,The predictive significance of chromobox family members in prostate cancer in humans. In Cell Oncol (Dordr) on 2024 Aug by
Xiaoting Xu, Cong Lai,et al..PMID:38427207
, (2024),
PMID:
38427207