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Location： Home > Polyclonal Antibodies > FGF7 Antibody

FGF7 Antibody#31162

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Product Detail

Product NameFGF7 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

ApplicationsELISA WB IHC

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of total FGF7 protein.

Immunogen TypePeptide

Immunogen DescSynthetic peptide corresponding to a region derived from 179-182 amino acids of Human Fibroblast growth factor 7

Target NameFGF7

ConjugateUnconjugated

Other NamesFibroblast growth factor 7 , KGF, HBGF-7

Accession NoSwiss-Prot:P21781
Gene ID:2252;

Uniprot P21781

Gene ID 2252;

Concentration0.4mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C/1 year

Application Details

Predicted MW: 23kd
ELISA: 1:500-1:5000
Western blotting: 1:1000-1:3000
Immunohistochemistry: 1:50-1:200

Gel: 10%SDS-PAGE
Lane1: Human gastric cancer tissue lysate
Lane2: Human esophagus cancer tissue lysate
Lysate: 40ug
Primary antibody: 1/1250 dilution
Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/5000 dilution
Exposure time: 1 second
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 31162 (FGF7 Antibody) at dilution 1/15, on the right is treated with the synthetic peptide.

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

If you have published an article using product 31162, please notify us so that we can cite your literature.

et al,Maldevelopment of the submandibular gland in a mouse model of apert syndrome.In Dev Dyn. On 2018 Nov by Yamaji K, Morita J et al..PMID:30251381 , (2018),
PMID: 30251381
et al,Maldevelopment of the submandibular gland in a mouse model of apert syndrome.In Dev Dyn. On 2018 Nov by Yamaji K, Morita J et al..PMID:30251381 , (2018),
PMID: 30251381
et al,Ser252Trp mutation in fibroblast growth factor receptor 2 promotes branching morphogenesis in mouse salivary glands. In J Oral Biosci on 2024 Mar by Daiki Iwata, Kaori Kometani-Gunjigake,et al..PMID:38246420 , (2024),
PMID: 38246420
et al,Integrating single-cell and spatial analysis reveals MUC1-mediated cellular crosstalk in mucinous colorectal adenocarcinoma , (2024),
PMID:
et al,Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice , (2024),
PMID:

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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