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Location： Home > Polyclonal Antibodies > P2RY11 Antibody

P2RY11 Antibody#31254

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Product Detail

Product NameP2RY11 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

ApplicationsELISA WB IHC

Species ReactivityHu

SpecificityThe antibody detects endogenous level of total P2RY11 protein.

Immunogen TypePeptide

Immunogen DescSynthetic peptide corresponding to a region derived from 361-374 amino acids of Human purinergic receptor P2Y, G-protein coupled, 11

Target NameP2RY11

ConjugateUnconjugated

Other Namespurinergic receptor P2Y, G-protein coupled, 11, P2Y11

Accession NoSwiss-Prot:Q96G91
Gene ID:5032;

Uniprot Q96G91

Gene ID 5032;

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C/1 year

Application Details
Predicted MW: 40kd
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
Gel: 10%SDS-PAGE
Lane1: Hela cell lysate
Lane2: 293T cell lysate
Lysates: 40 ug per lane
Primary antibody: 1/500 dilution
Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Exposure time: 1 minute
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31254 (P2RY11 Antibody) at dilution 1/40, on the right is treated with the synthetic peptide.
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.

If you have published an article using product 31254, please notify us so that we can cite your literature.

et al,Inhibition of P2Y11R ameliorated TNF-α-Induced degradation of extracellular matrix In human chondrocytic SW1353 cells. In Am J Transl Res on 2019 Apr 15 by Wang D, LIn N,et al.. PMID: 31105822 , (2019),
PMID: 31105822

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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