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Location： Home > Polyclonal Antibodies > VEGFA Antibody

VEGFA Antibody#31274

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Product Detail

Product NameVEGFA Antibody

Host SpeciesRabbit

ClonalityPolyclonal

ApplicationsELISA WB IHC

Species ReactivityHu

SpecificityThe antibody detects endogenous level of total VEGFA protein.

Immunogen TypePeptide

Immunogen DescSynthetic peptide of human VEGFA

Target NameVEGFA

ConjugateUnconjugated

Other Namesvascular endothelial growth factor A, VPF, VEGF, MVCD1

Accession NoSwiss-Prot:P15692
Gene ID:7422;

Uniprot P15692

Gene ID 7422;

Calculated MW27 kDa

Sdspage MW35kd

Concentration0.8mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C/1 year

Application Details

WB 1:500-1:2000
IHC 1:50-1:200
ELISA 1:5000-1:10000

Gel: 8%SDS-PAGELysate: 40 ugLane: Hela cell lysatePrimary antibody: (VEGFAAntibody) at dilution 1/600Secondary antibody: Goat anti rabbit IgG at 1/5000 dilutionExposure time: 2 minutes
The image on the left is immunohistochemistry of paraffin-embeddedHuman liver cancer tissue using (VEGFA Antibody) at dilution 1/50

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

If you have published an article using product 31274, please notify us so that we can cite your literature.

et al,Artesunate Inhibits Proliferation and Invasion of Mouse Hemangioendothelioma Cells in vitro and of Tumor Growth in vivo.In Oncol Lett on 2017 Nov by Ning Wang , Hongxia Chen,et al..PMID: 29113263 , (2017),
PMID: 29113263
et al,Photoacoustic molecular imaging-escorted adipose photodynamic-browning synergy for fighting obesity with virus-like complexes. In Nat Nanotechnol on 2021 Apr by Ronghe Chen, Shanshan Huang,et al..PMID:33526836 , (2021),
PMID: 33526836
et al,Interleukin-17 and vascular endothelial growth factor: new biomarkers for the diagnosis of papillary thyroid carcinoma in patients with Hashimoto’s thyroiditis. In J Int Med Res on 2022 Jan by Shuiping Li, Shilin Li,et al..PMID: 35023376 , (2022),
PMID: 35023376
et al,3D printed PGCL@PLA/10CSPL composite scaffolds loaded with fibronectin 1 for intervertebral disc degeneration treatment, In Biofabrication on 2024 Dec 13 by Weilin Zhang, Siyuan Chen,et al..PMID:39668784 , (2024),
PMID: 39668784

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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