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Location： Home > Polyclonal Antibodies > RSPO1 Polyclonal Antibody

RSPO1 Polyclonal Antibody#31496

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Product Detail

Product NameRSPO1 Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human RSPO1 (NP_001033722.1).

ConjugateUnconjugated

Other NamesRSPO1;CRISTIN3;RSPO

Accession NoUniprot:Q2MKA7
GeneID:284654

Uniprot Q2MKA7

Gene ID 284654

Calculated MW29kDa

Sdspage MW29KDa

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200
Western blot analysis of extracts of SKOV3 cells, using RSPO1 antibody.
Western blot analysis of extracts of Rat pancreas, using RSPO1 antibody.
Immunofluorescence analysis of A549 cells using RSPO1 Rabbit pAb.
Immunofluorescence analysis of NIH-3T3 cells using RSPO1 Rabbit pAb.
Immunofluorescence analysis of C6 cells using RSPO1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat ovary using RSPO1 Rabbit pAb.
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

If you have published an article using product 31496, please notify us so that we can cite your literature.

et al,Prognostic prediction and diagnostic role of Rspondin 1 expression in esophageal squamous cell carcinoma. In Indian J Pathol Microbiol on 2024 Jun 8 by Xiaoxia Cheng, Jiao Liu, et al..PMID:38864442 , (2024),
PMID: 38864442

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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