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IL34 antibody#31957

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Product Detail

Product NameIL34 antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification

ApplicationsWB, IHC

Species ReactivityHu

Immunogen DescSynthetic peptide of human IL34

Target NameIL34

ConjugateUnconjugated

Other NamesIL-34; C16orf77

Accession NoNCBI Protein#:NP_001166243

Uniprot Q6ZMJ4

Gene ID 146433

Calculated MW27 kDa

Concentration0.9mg/ml

FormulationpH7.4 PBS, 0.05% NaN3, 40% Glycerol

StorageStore at -20˚C/1 year

Application Details
WB dilution:1:200-1:1000
IHC dilution:1:30-1:150
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue and Human cerebella tissue lysates, Primary antibody:IL34 Antibody at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (IL34 Antibody) at dilution 1/30.
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

If you have published an article using product 31957, please notify us so that we can cite your literature.

et al,Stigmasterol alleviates neuropathic pain by reducing Schwann cell‐macrophage cascade in DRG by modulating IL‐34/CSF1R. In CNS Neurosci Ther on 2024 Apr by Waimei Si, Zhenni Chen, et al..PMID:38572785 , (2024),
PMID: 38572785

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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