Product Detail
Product NameSTAT1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total STAT1 protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human STAT1 (NP_644671.1).
Target NameSTAT1
ConjugateUnconjugated
Other NamesCANDF7;IMD31A;IMD31B;IMD31C;ISGF-3;STAT91;STAT1 alpha;STAT1
Accession NoUniprot:P42224
GeneID:6772
Uniprot
P42224
Gene ID
6772
Sdspage MW84KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human lung cancer using STAT1 Rabbit pAb.
Western blot analysis of extracts of various cell lines, using STAT1 antibody.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
If you have published an article using product 32001, please notify us so that we can cite your literature.
et al,Effect of silencing CD147 on glycolysis in prostate cancer LNCaP cells
, (2023),
PMID:
Yes
